In a slow cooker stir cranberry sauce, dried cranberries, orange juice, cinnamon, and orange zest until combined. Set pork loin in the middle of sauce mixture and drizzle sauce over meat.
Cover and cook on low 4 hours or until meat reaches a temperature of 140°F to 145°F.
Transfer pork to a cutting board. Remove twine and slice.
Strain cranberries from slow cooker; cover and set aside. Pour strained liquid into a skillet. Add salt and pepper to taste. Simmer 7 to 8 minutes. Spoon reserved cranberries and sauce over pork loin.